Downstream Processing Engineer for Fermentation Optimization

2 semanas atrás


Braga, Braga, Portugal Silicolife Tempo inteiro

SilicoLife is a pioneer in biotechnology, harnessing the power of computational biology to produce valuable compounds through sustainable fermentation processes. Our company has been at the forefront of innovation, collaborating with top industry players and research institutions for over a decade.
We have received significant investments, driving our shift towards becoming a product-focused company, allowing us to exclusively focus on creating high-value internal intellectual property and delivering cutting-edge products to the rapidly growing supplements market.
This extraordinary opportunity allows you to be part of our journey, joining a team that values diversity, equity, and inclusion.

Job Description:

You will play a crucial role as a Downstream Processing (DSP) Engineer for Fermentation Optimization, working closely with our bioprocess development team to design, model, and optimize downstream processes for precision fermentation and microbial cell cultures. You will apply your expertise in DSP operations and bioprocess simulation tools to create scalable, cost-effective workflows that enhance our production efficiency and meet the demands of a dynamic, high-growth market.

Responsibilities:
  • Collaborate with R&D, process engineering, and production teams to develop and optimize DSP workflows for fermentation-based production
  • Utilize bioprocess simulation tools (e.g., SuperPro Designer, Aspen) to model processes, analyze data, and improve production efficiency
  • Design and test DSP strategies, including filtration, chromatography, centrifugation, and other purification techniques, to meet target yields and purities
  • Conduct scale-up studies and simulations to ensure reproducibility and scalability of downstream processes
  • Evaluate and mitigate risks associated with DSP methodologies and ensure compliance with regulatory standards
Requirements:

To succeed in this position, you should possess:

  • Bachelor's or Master's degree in Bioprocess Engineering, Chemical Engineering, or related field (PhD is a plus)
  • Proven experience with DSP methods such as filtration, chromatography, and centrifugation
  • Proficiency in bioprocess simulation software (e.g., SuperPro Designer, Aspen)
  • Strong analytical and data interpretation skills, with experience in scaling processes for industrial applications
  • Knowledge of regulatory standards and compliance for bioprocessing
Benefits:

We offer a competitive salary of $120,000 - $160,000 per year, depending on your experience. Additional benefits include a flexible work schedule, extra vacation days, health insurance, and participation in internal talks, company retreats, and events. We strive to create a positive and supportive work environment that values diversity, equity, and inclusion.



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