Postdoc In Inflammation

2 semanas atrás

Porto, Portugal Institut Pasteur Tempo inteiro

Organisation/Company: Institut Pasteur
Department: Immunology
Research Field: Biological sciences » Biology
Researcher Profile: First Stage Researcher (R1)
Positions: Postdoc Positions
Country: France
Application Deadline: 29 Nov 2024 - 12:00 (Europe/Paris)
Type of Contract: Temporary
Job Status: Full-time
Offer Starting Date: 2 Dec 2024
Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure? No
Offer Description Our laboratory has one position available for a postdoctoral fellow in the area of inflammation and regenerative disease research. We are interested in mechanisms of immunoregulation and tissue adaptation to external challenges, with an emphasis on tissue long-lived cells such as stromal cells, and their crosstalk with immune cells, stem cells, and the vasculature. We perform mostly in vivo studies, combining lineage tracing and depletion models, flow cytometry, confocal microscopy, and unbiased approaches such as single-cell transcriptomics and epigenetics to characterize molecular and cellular mechanisms. Using these approaches, we previously identified an essential role for specific subsets of stromal cells in tissue repair and cancer immunity (Dulauroy et al., Nature Medicine 2012; Stzepourginski et al., PNAS 2017; Jacob et al., Cell Stem Cell 2022; Di Carlo et al., Nature Immunology 2023). Building on these findings, we aim at identifying novel mechanisms regulating tissue response to injury, with a focus on stromal immunoregulation and plasticity in organs with high remodeling capacity such as the skin, skeletal muscle, or adipose tissue.
Where to apply E-mail: ******
Requirements Research Field: Biological sciences » Biology
Education Level: PhD or equivalent
Required qualifications: Recent PhD or MD/PhD degree in vascular biology, immunology, or related biomedical field, with a track record of publications and lab experience in one or more areas that include: vascular biology, innate immunity, stromal/mesenchymal stem cells, and tissue repair. Highly motivated candidates with interest in areas of research at the intersection of immunology, vascular biology, and stromal/stem cell biology are strongly encouraged to apply.
Specific Requirements:
Required : Solid experience with in vivo rodent models and flow cytometry
Desirable : Previous experience in confocal microscopy and/or transcriptomics data analysis
Would be a plus : Previous experience in scripting languages (R) and Seurat.

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