Principal Clinical Scientist
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About The Role
What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI reasons about medical evidence for millions of patients worldwide?
We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research workflows. In this role, your deep knowledge of regulatory-grade clinical data will help ensure that the AI systems influencing biomedical research are built on a foundation of scientific integrity — the kind that holds up to real-world scrutiny.
This is a fully remote, flexible contract role designed for experienced clinical scientists who want meaningful, high-impact work on their own schedule.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and critically review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
- Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
- Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
- Provide expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
- Help establish the scientific credibility of AI outputs in clinical and biomedical contexts
Who You Are
- Senior-level professional with hands-on experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent global bodies
- Strong background in clinical research methodology, biostatistics, or translational science
- Naturally rigorous — you hold AI-generated content to the same standards you'd apply in a real submission
- Self-directed and comfortable delivering high-quality work independently
Nice to Have
- Prior experience with data annotation, data quality evaluation, or AI training workflows
- Familiarity with AI tools or clinical NLP systems as an end user
- Experience spanning multiple therapeutic areas or regulatory jurisdictions
- Background in academic clinical research, CRO environments, or regulatory consulting
Why Join Us
- Work directly on frontier AI systems that are reshaping clinical and biomedical research
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, expert-level work
- Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale
- Potential for ongoing work and contract extension as new projects launch
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