Call for Research Grant Assignment

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funchal, ilha da madeira, Portugal Universidade De Coimbra Tempo integral

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Organisation/Company Universidade de Coimbra Department Divisão de Projetos e Atividades (Bolsas) Research Field Chemistry » Other Researcher Profile First Stage Researcher (R1) Positions Master Positions Application Deadline 20 Oct 2026 - 23:59 (Europe/Lisbon) Country Portugal Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Nov 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The University of Coimbra opens a call for the assignment of a research grant, with 1 position(s), under the project UID/00313/2025, title Coimbra Chemistry Centre (CQC).

The call is governed by this Notice of Opening, the University of Coimbra Research Grant Regulations (RBI-UC), subsidiarily by the Research Grant Regulations of the Foundation for Science and Technology (RBI-FCT), by the Research Fellow Statute (EBI), by the Norms for Grant Assignment and Management within R&D Projects, by the Code of Administrative Procedure (CPA), all in their current wording, and by other applicable national and community legislation.

Procedure Reference: IT

I.I - Grant Recipients

Master’s degree holders, in Medicinal Chemistry, enrolled in a doctoral degree, in the scientific area of Chemistry.

I.II -

Ineligible candidates:

I.III -

Eligible for grant assignment if meeting the requirements:

a) Portuguese nationals or nationals of other EU Member States
b) Nationals of third countries
c) Stateless persons
d) Beneficiaries of political refugee status

When the work plan takes place, in whole or in part, in foreign institutions, only candidates who can prove permanent and habitual residence in Portugal at the start of the grant are eligible.

II - Grant location

Department of Chemistry of the Faculty of Science and Technology of the University of Coimbra

IV - Work Plan / Goals to be achieved

Development of a new photosensitizer for photodynamic cancer therapy, recently patented by the University of Coimbra. The studies include the photochemical characterization of the compound, in vitro phototoxicity—including the use of spheroids—and in vivo photodynamic therapy, including characterization of the tumor microenvironment in various animal models. Studies will be conducted in cell cultures to evaluate mechanisms of cell death, including the use of confocal fluorescence microscopy and super-resolution microscopy. The in vivo studies will include pharmacokinetics, biodistribution, toxicity (including phototoxicity), and conventional photodynamic therapy as well as photodynamic therapy using pulsed lasers (Flash-PDT) with ascending doses and for various time intervals between photosensitizer administration and tumor illumination. Combinations with other therapeutic agents, particularly immunotherapy, will also be evaluated.

V.I - Renewal Possibility

Possibily renewable

VI - Funding and financial conditions of the grant VI.I - Monthly grant amount (paid by

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