Postdoctoral Researcher in Glycofoldamers for Bacterial Toxin Inhibition
Há 16 horas
**Job Overview**
We are seeking a highly motivated postdoctoral researcher to join our team at the Instituto De Tecnologia Química E Biológica António Xavier Itqb Nova. Our research focuses on the development of glycofoldamers as bacterial toxin inhibitors.
**Estimated Salary**: €25,000 - €35,000 per annum, depending on experience.
**Job Description**
The selected candidate will explore a new class of multivalent glycoconjugates for bacterial toxin/adhesin inhibition. Key responsibilities include:
- Preparing and purifying oligomeric multivalent scaffolds
- Conjugating them with carbohydrate ligands
- Characterizing the interaction between the glycoconjugates and toxins/adhesins by biophysical techniques
- Elucidating the structure of the complexes formed
- Evaluating the inhibition of adhesion to host cells
**Required Skills and Qualifications**
We are looking for candidates with a Master's degree in Chemistry, Biochemistry, Pharmaceutical Sciences or related areas, with a strong background in organic synthesis, solid-phase synthesis, and analytical and preparative HPLC. Experience in glycochemistry and a good understanding of biophysical techniques are essential.
**Benefits**
This is a full-time position, renewable for up to 6 months, with a possibility of extension. The work will be carried out in the Bio-oriented Supramolecular Chemistry laboratory at ITQB NOVA, under the supervision of Doctor Pedro Mateus.
**Others**
The selected candidate will have the opportunity to contribute to cutting-edge research in the field of glycoscience and develop their skills in a collaborative environment. We offer a dynamic and supportive team, with access to state-of-the-art facilities and resources.
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