Research Scientist Position

Há 7 dias


Lisboa, Lisboa, Portugal Ibet Portugal Tempo inteiro

Job Description

We are seeking a highly motivated and skilled researcher to join our team at Instituto de Biologia Experimental e Tecnológica (iBET) in Portugal. The successful candidate will work on the project 'Immunopredict – Immune cell assays for prediction of immunogenicity of recombinant Adeno-associated virus (rAAV)', which aims to develop and implement in vitro assays using mononucleated cells from peripheral blood to study the immunogenicity of biological therapeutic agents.

The research fellow will be responsible for developing in vitro assays using cells selected from peripheral blood mononucleated cells from buffy coats, with the aim of studying the response of immune system cells to viral vectors (rAAVs) for gene therapy. Specifically, they will investigate the activation of monocyte-derived dendritic cells and consequent activation of T cells after stimulation with viral vectors with different characteristics to predict their immunogenicity and understand the immunogenic response to new therapeutic modalities.

The ideal candidate should have a strong background in Biomedical Sciences, with experience in animal cell culture, molecular biology methods, analytical techniques, and relevant software for data analysis and visualization. Results-oriented, motivated, self-driven, and a team player, the successful candidate should also possess good spoken and written English expression and immediate availability.



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