Senior Bioinformatics Research Scientist

Há 6 dias


Porto, Porto, Portugal Institut Curie - Research Center Tempo inteiro

About Institut Curie

Institut Curie is a pioneering research center dedicated to the advancement of medical sciences, particularly in the field of cancer research. Our commitment to innovation and excellence has made us a leading player in the global scientific community.

Job Overview

We are seeking an exceptional Senior Bioinformatics Research Scientist to join our esteemed team at Institut Curie. This is a unique opportunity to contribute to groundbreaking research focused on deciphering pediatric brain tumor resistance.

About the Role

The selected candidate will be part of the ENCOURAGER project, a collaborative effort funded by Fight Kids Cancer. As a Senior Bioinformatics Research Scientist, you will investigate the longitudinal evolution of gliomas under treatment with multi-omic profiling of pediatric glioma PDX models at single-cell resolution. Your primary responsibility will be to drive and develop a scientific project focused on tumor heterogeneity/treatment resistance.

Key Responsibilities

  • Perform end-to-end data analysis: QC, processing, results, visualization, interpretation...
  • Analyze single-cell RNA-seq and single-nucleus ChIP-seq datasets
  • Perform high-dimensional data analysis and integrative 'omic' data analysis
  • Use and develop methods and strategies to investigate treatment resistance mechanisms

Requirements

  • PhD in bioinformatics, statistics, or computer science with knowledge and interest in biology
  • Strong foundation of knowledge in one or more of the following: genomics, cancer biology, statistics
  • Evidence of scientific accomplishment via peer-reviewed publications
  • Excellent computational skills
  • Experience working in a Unix environment
  • Experience in statistical analysis using R
  • Experience with high-throughput sequencing data analysis
  • Proficiency in English and excellent scientific writing skills

Benefits

  • Fixed-term contract for 18 months
  • Full-time position
  • Competitive salary (approximately €40,000 - €50,000 per year)
  • 70% reimbursement of annual travel costs
  • Company health insurance scheme

About Us

Institut Curie is committed to fostering a culture of diversity, equity, and inclusion. We offer a dynamic and supportive work environment that encourages collaboration and professional growth.



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