Postdoctoral Researcher in Protein Post-Translational Modifications
Há 5 dias
Seeking a highly motivated postdoctoral researcher to join our interdisciplinary team at the Centre de Biophysique Moléculaire, CNRS. Our research focuses on understanding the molecular mechanisms of protein post-translational modifications (PTMs), particularly SUMOylation and ubiquitination, in cancer development.
About the Project:
The successful candidate will work under the supervision of Dr. Marcin Suskiewicz and Dr. Ibtissam Talhaoi on a project funded by the ERC, 'SUMOwriteNread' (grant id 101078837). The project aims to elucidate the biochemical and structural characterization of selected E3 ligases and their substrates, with a focus on nucleosome/chromatin.
Key Responsibilities:
- Biochemistry and molecular biology techniques
- Protein and DNA purification, cell biology
- Preparation of samples for electron-microscopy and cryo-EM, observation and analysis of DNA-protein complexes and chromatin
- Interpretation of results and writing of articles
- Presentation of results at conferences and scientific events
Requirements:
- Ph.D. in Biological sciences or related field
- Strong experience in post-translational modifications of proteins, especially SUMOylation and ubiquitination
- Solid expertise in in vitro chromatin reconstitution
- Knowledge of biochemistry and molecular biology techniques
- Previous experience in cell biology an advantage but not essential
Location and Benefits:
The position is based at the Centre de Biophysique Moléculaire, CNRS campus in Orléans, France. The centre provides a dynamic and interactive working environment with state-of-the-art facilities. The postdoc will benefit from our support in applying for postdoctoral fellowships to continue working on this project beyond the initially planned period.
Salary: €45,000 - €50,000 per annum, depending on qualifications and experience.
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