Postdoctoral Researcher
Há 2 dias
The CNRS is seeking a highly skilled Postdoctoral Researcher to join its Laboratoire des Interactions Plantes Microbes Environnement. The successful candidate will work on a 24-month project funded by the ERC, investigating the effect of host genetics on pathogen-pathogen interactions in the plant Arabidopsis thaliana.
This project aims to integrate large-scale field observations with experimental tests of host-dependent interactions among microbes. The postdoctoral researcher will set up genome-wide association studies (GWAS) in vitro and field conditions, and functionally validate several quantitative trait loci (QTLs) using modern plant genome editing tools such as CRISPR/Cas9.
Working with a panel of 200 Illumina whole-genome sequenced A. thaliana accessions from southwest France, including 50 accessions sequenced with PacBio technology, the postdoctoral researcher will test the effect of natural accessions of A. thaliana on six pairs of pathogenic strains under in vitro and field conditions.
Field conditions will be tested in the USA, with three to four stays of six weeks each. The postdoctoral researcher will also collaborate with research groups at the Max Planck Institute and New York University, and will be responsible for setting up GWA mapping experiments and validating QTLs using advanced plant genome editing tools.
The ideal candidate will possess excellent skills in molecular biology, particularly in validating candidate genes underlying plant QTLs affecting pathogen-pathogen interactions. A strong background in quantitative genetics, experimental design, and statistical analysis is advantageous. Fluency in English is required.
**Estimated Salary:** €45,000 - €60,000 per annum, depending on experience, plus benefits.
This role offers an exciting opportunity to contribute to cutting-edge research in plant pathology and microbiology, and to develop expertise in GWAS and plant genome editing technologies.
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