Molecular Modeling of DNA Damage: A Research Opportunity in Biophysics
Há 4 dias
About the Job: We are seeking a highly motivated PhD candidate to join our research team at the University of Lille, specializing in biophysics. The successful candidate will have the opportunity to work on an exciting project titled 'DNASTRIX,' which aims to investigate and quantify how nuclear mechanics can be altered by forces issued from the cellular environment.
About the Project: Our project focuses on understanding the mechanical link between extranuclear cell structures and nucleus, as well as chromatin reorganization and possible damage to chromatin and DNA from mechanical forces. The main subject of this PhD grant is centered on the theory and modeling part of the work, where you will develop molecular models of cytoskeletal and nucleoskeleton proteins involved in stress transmission to the nucleus.
Your Role: As a PhD researcher, you will work closely with our team to design, develop, and apply innovative techniques based on micro-electromechanical systems (MEMS) devices. You will also leverage theoretical and computer modeling programs of all-atom and coarse-grained molecular dynamics to elucidate the multi-scale details of mechanical stress transfer to the nuclear constituents.
About the Team: Our research team is located at the University of Lille, France, within the Department of IEMN CNRS. We are a collaborative and dynamic group of researchers passionate about advancing knowledge in biophysics and its applications.
What We Offer: The University of Lille offers a competitive salary range of €1,500 - €2,000 per month, depending on experience. Additionally, you will have access to excellent working conditions, including state-of-the-art research facilities and equipment. You will also have the opportunity to engage in professional development opportunities and collaborate with international partners.
About the Location: Lille is a vibrant city located in northern France, offering a unique blend of French culture and European charm. With a rich history, beautiful architecture, and a thriving cultural scene, Lille is an excellent place to live and work.
Requirements: To be eligible for this position, you must have a Master's degree or equivalent in physics, chemistry, biology, or a related field. You should also have a strong background in biophysics, computational skills, and fluency in Unix/Linux OS. English language proficiency is mandatory, and French language proficiency is desirable but not required.
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