Laboratory Technician – Advanced Omics Platforms
Há 1 mês
Laboratory Technician – Advanced Omics Platforms (AOP) We are seeking a Laboratory Technician for the Advanced Omics Platforms (AOP) to provide technical services to support the operation of the Botton-Champalimaud Pancreatic Cancer Centre.
Duties and Responsibilities Main duties will include:
Perform laboratory protocols to produce reliable and precise data to support scientific research;
Perform routine laboratory protocols in accordance with Standard Operating Procedures (SOPs);
Handle fresh and archival (fresh frozen and FFPE) patient material;
Prepare high-quality DNA and RNA from human specimens and samples according to SOPs;
Perform quality control of DNA and RNA preparations according to SOPs;
Perform data entry and sample tracking using Laboratory Information Management Systems (LIMS);
Produce accurate reports on DNA and RNA sample quality control;
Prepare Next Generation Sequencing (NGS) libraries both manually and using automated liquid handling robotics;
Troubleshoot and optimize library preparation protocols;
Operate and maintain NGS platforms (e.g., Illumina, Oxford Nanopore, and 10X Genomics) and related equipment;
Efficiently resolve and document technical issues in a timely and clear manner;
Develop positive relationships with internal teams and stakeholders;
Ensure the care and cleanliness of the AOP designated lab space to comply with Quality System Regulation requirements;
Work with other members of the AOP to help maintain laboratory stocks of kits, reagents, and other consumable requirements;
Participate in routine lab meetings and contribute to the planning and execution of research projects.
Skills - Qualifications: MSc, PhD, or other post-graduate level qualification in life or medical sciences;
- 4-10 years of research experience;
- Good scientific knowledge with demonstrated ability to perform routine laboratory protocols accurately and efficiently;
- Experience in extracting DNA and RNA from fresh frozen or fixed material;
- Demonstrated experience in using standard molecular techniques including cloning and PCR;
- Experience in following SOPs and experimental workflows accurately and efficiently;
- Experience in using and analyzing results obtained from PCR and Real-time PCR machines;
- General IT proficiency with the ability to generate basic reports;
- Good communication and organizational skills.
Specific Requirements (Desirable) - Proficient in both English and Portuguese;
- Experience in NGS library preparation, either manually or using automated liquid handling robotics;
- Experience in running and maintaining NGS instruments such as Illumina's NovaSeq6000;
- Experience in handling patient specimens and/or samples;
- Experience in data entry and sample tracking using LIMS;
- Experience in using QIAcube or equivalent platform;
- Experience in using TapeStation or equivalent platform for assessing DNA and/or RNA quality;
- Experience with document management systems.
Maximum Allowable Duration of the Fellowship Contract 12 months with the possibility of renewal.
Eligibility Criteria National, Foreign or Stateless candidate(s) who hold a degree in a relevant field and professional curriculum that reveals a profile appropriate to the activity to be developed.
How to Apply Candidates must provide:
A completed standard application form - Call Ref. "BCPCC_AOP"
A letter of motivation (max. 2 pages), highlighting your suitability for the role, salary expectations, and notice period
CV (max. 2 pages)
Names and contact information for at least 2 references. If you do not wish that we contact current or past employers, please state so and why in your letter of motivation.
Evaluation and Selection Criteria All CVs and motivation letters will be reviewed by the selection committee. Reference letters will be requested from shortlisted candidates, and those candidates deemed particularly well suited for the position will be invited for an interview.
Notification of Results All candidates will receive a receipt of acknowledgment within 7-10 business days. The highest scoring candidate will be notified by email or telephone. All other candidates will be notified solely by email of the outcome of the recruitment process.
After being notified, candidates will have 10 working days to present a claim for redress by email (******). If no claim is received by the Champalimaud Foundation, the Evaluation Committee's decision will become definitive.
About Us The Botton-Champalimaud Pancreatic Cancer Centre is a state-of-the-art facility comprising research laboratories, a day hospital, a surgical centre, as well as inpatient and intensive care facilities. The mission of the Botton-Champalimaud Pancreatic Cancer Centre is to develop new and effective treatments for pancreatic cancer. To accomplish this goal, a multidisciplinary team of surgeons, clinicians, clinical trials specialists, cancer scientists, genomics experts, and computational biologists work together to deliver world-leading outcomes for patients with pancreatic cancer.
The Botton-Champalimaud Pancreatic Cancer Centre is also closely integrated with the Champalimaud Centre for the Unknown. Members of the Champalimaud Research Programme (CR) and the Champalimaud Clinical Centre (CCC) work together to investigate fundamental biological processes and search for effective solutions to alleviate the burden of oncological, neurological, and mental diseases, while providing state-of-the-art care to the patients of the CCC. With 479 members, including group leaders, postdocs, PhD and MSc students, research technicians, and highly specialised research staff, the CR community encompasses 39 nationalities. Within the Lisbon Ocean Campus, CF will expand its research, technological development, innovation, and clinical practice in the digital therapeutics field.
Additional Institutional Information: In line with our community guidelines and Equality, Diversity and Inclusion policy and Gender Equality Plan, no candidate may be privileged, favoured, prejudiced, or deprived of any right or excluded from any duty on the basis of age, sex, gender identity, sexual orientation, race/ethnicity, disability, chronic illness, language, nationality, territory of origin, family status (marital, pregnancy and maternity, having or not having dependents), socioeconomic situation, education, religion, political or ideological beliefs, trade union membership, or on any other grounds which are irrelevant to decision-making.
The present call has the sole purpose of filling the indicated research position. This call may be canceled at any time on or before the jury's evaluation of all eligible candidates and the recruitment process shall be concluded on the day of the full execution of the contract between the Champalimaud Foundation and the selected candidate.
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Lisboa, Portugal Fundação Champalimaud Tempo inteiro.Laboratory Technician – Advanced Omics Platforms (AOP)Localização: Botton-Champalimaud Pancreatic Cancer CenterEntidade Empregadora: Fundação ChampalimaudRegime: Tempo InteiroPosição: TécnicoInício da Candidatura: 25 Jun. 2024We are seeking a Laboratory Technician for the Advanced Omics Platforms (AOP) to provide technical services to support the...
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