Unlocking the Secrets of Transcription Regulation

2 semanas atrás


Porto, Porto, Portugal Igbmc Tempo inteiro

Company Overview: Located in Strasbourg, France, the Institute for Genetics, Molecular and Cellular Biology (IGBMC) is a renowned European center for biomedical research. Our organization boasts an international and attractive research environment, featuring approximately 45 research groups and 17 technological platforms.

Job Description: A postdoctoral position is currently available in the group of László Tora and Stéphane D. Vincent at IGBMC. The primary focus of this role involves investigating the post translation modification (PTM) of core histone proteins, which play a crucial role in transcription regulation. This research aims to understand how histone writers function with their accessory subunits to bind and modify specific histone tail sites, thereby regulating chromatin accessibility and dynamics.

Key Objectives:

  • Determine how chromatin properties regulate reading and writing by mammalian HAT complexes (SAGA and ATAC).
  • Elucidate how the different subunits of the related SAGA and ATAC HAT complexes control their differential targeting and transcription activity.

Required Skills and Qualifications:

  • Strong expertise in molecular biology.
  • Additional experience in genome-wide data analyses is necessary.

Benefits: As a highly motivated and interactive candidate, you will have the opportunity to contribute to the success of our project. You will also be part of a dynamic and collaborative research environment.

Estimated Salary: €2,300-€2,500 per month (gross salary). The contract duration is one year, renewable up to three years.



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