Research Scientist: Measuring Evolutionary Imprints of Gene Regulation

2 semanas atrás


Porto, Porto, Portugal Cnrs Tempo inteiro
About CNRS

CNRS is a French public research organization dedicated to scientific research. As a leading international research center, CNRS focuses on advancing knowledge in various fields, including biology.

Salary and Benefits

The salary for this position is estimated at €30,000-€40,000 per year, depending on qualifications and experience. The contract duration is 12 months, renewable for an additional 12 months.

About the Job

This postdoctoral position is located at the Institute of Human Genetics (IGH) in Montpellier, France. The hosting team is 'Systemic impact of small regulatory RNAs' led by Hervé Seitz.

We are looking for a highly motivated individual to work on measuring the evolutionary imprints of gene regulation by microRNAs. The project aims to explore situations where a miRNA has been lost or gained in a given animal clade, and evaluate which sites are only conserved in the presence of the miRNA.

Key responsibilities include extraction of 3′ UTR sequences for candidate target genes in various species, alignment, measurement of selection pressure on each complementarity site in each clade of interest, and comparison of selective pressure on miRNA complementary sites between clades of the same evolutionary age or different ages.

Required Skills and Qualifications
  • PhD degree in bioinformatics or molecular phylogeny with a clear interest in the other field.
  • Programming skills in bash, Perl, and R.
  • Basic knowledge in molecular genetics and phylogenetics.
Benefits and Opportunities

The hosting institute is a dynamic and international environment with around 200 people from diverse backgrounds. The lab offers great training opportunities in both bioinformatics and experimental biology.

Our team values cooperativity and transparency, sharing openly our scripts and datasets for reproducible results. We deposit our manuscripts on public servers like bioRxiv and HAL for immediate open access.



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