Unlock the Secrets of Kinase Activity in Giant Viruses

3 semanas atrás


Porto, Porto, Portugal Cnrs Tempo inteiro

About the Company: CNRS, a renowned research organization, invites applications for a PhD Project focused on developing fluorescent biosensors to detect kinases in giant viruses.

Job Summary: This thesis project will explore the role of phosphorylation in viral cycles, combining biochemical and structural approaches. The successful candidate will develop selective biosensors for sensitive detection of viral kinase activities and apply them to study functions in vitro and in vivo.

Responsibilities:

  • Develop novel fluorescent peptide biosensors for characterizing viral protein kinase activity
  • Apply these tools to investigate kinase functions in the viral cycle and host infection process
  • Screen small molecule libraries to identify inhibitors for blocking specific steps in the viral infection cycle

Requirements: To be considered for this position, candidates should have a strong background in biochemistry or a related field. Familiarity with biochemical and structural approaches is essential, as well as expertise in substrate peptides and reporter biosensors. First-stage researcher (R1) profile preferred.

Benefits: As a full-time employee, you will enjoy a competitive salary and benefits package. Enjoy working in a dynamic team environment, collaborating with experts in their fields. Opportunities for professional growth and development within the research infrastructure.

Salary: €35,000 - €50,000 per annum, commensurate with experience.



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