Exploring RNA-Lipid Nanoparticle Interactions for Therapeutic Advancement

2 semanas atrás


Porto, Porto, Portugal Laboratoire De Bioimagerie Et Pathologies Umr7021 - Cnrs Tempo inteiro

Company Overview

Laboratoire de Bioimagerie et Pathologies UMR7021 - CNRS is a renowned research institute dedicated to advancing our understanding of biological systems.

We are seeking a highly motivated PhD candidate to join our team and contribute to the development of innovative therapeutic solutions.

Salary

The successful candidate will be offered a competitive salary, estimated to be around €35,000 per annum, commensurate with their qualifications and experience.

Job Description

This PhD project focuses on investigating the structural characteristics of lipid nanoparticles (LNPs) as vectors for RNA delivery. LNPs have shown great promise in therapeutic applications, but their intracellular delivery remains a significant challenge.

The candidate will employ fluorescent probes with environmental sensitivity to local polarity, hydration, and viscosity to examine the morphological and biological characteristics of LNPs.

This project involves collaboration with two laboratories at the University of Lyon, integrating findings from diverse complementary approaches, including nuclear magnetic resonance (NMR) and electron microscopy.

Required Skills and Qualifications

The ideal candidate should have a strong background in biophysics, with knowledge of instrumental development and fluorescence microscopy techniques.

They should be motivated to learn and develop new skills, with good interpersonal skills and the ability to work effectively in a team environment.

Benefits

The successful candidate will have access to state-of-the-art research facilities and equipment, as well as opportunities for professional growth and development.

Others

The PhD position is available for 3 years, with a starting date of March 2025. The candidate will be based in Illkirch, France, and will work under the supervision of experienced researchers.



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